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White silo winery wedding9/25/2023 But the “Raspberry Festival” consisted of a kid at a table in the back selling a few overpriced food items containing raspberries from the While Silo Farm. The rolling hills along the border with New York are always pretty, especially so in the fall. Don’t get me wrong: the farm and the winery itself are absolutely beautiful. Sounds exciting! And a farm museum to boot!Īny excitement was quashed as we entered the tasting room. Live music, free farm museum, winery and field tours throughout the day. Raspberry S’mores, Brie Quesadillas with Jalapeno Rasberry Sauce, Raspberry Sorbet with Raspberry Scones, Grilled Chicken with Raspberries, Mixed Greens Raspberry Salad, and Raspberry Crisp are scheduled. We will be serving 6 small plates of food and desserts prepared with our farm grown raspberries. Our family visit would be during their “Raspberry Festival” which, again for inexplicable reasons, got us way more excited than it should have. Sure, I have an affinity of our lesser-known towns like Sherman, but that’s about it. I don’t know why, but I had built this place up in my head as being a special place over the years. I can’t tell you how many times I semi-planned to make it out here over the years… suffice it to say that number is pretty high. So let me start over… I threw the whole family in the car to head out to the second farthest winery – by one minute – in the state out in Sherman. White Silo clocks in at 69.3 miles away and 1 hour and 19 minutes away. more direct 2-lane roads), from our West Hartford compound, Saltwater Farm in Stonington is 69.5 miles and an hour and 20 minutes away according to Google Maps. Using the most efficient routes to each (that is, highway miles vs. Really and truly list-completion is my drug.Īnd so, with that in mind, I threw the whole family in the car to head out to the farthest away winery in the state – aha! I had always thought this was the case, but the researcher in me just decided to check. I wanted to make the point that writing CTMQ does not feel like a job at all. This site is as far from “corporate” as you can get, really. I can skip out on a place if my son is not cooperating and come back another day. I can wait a month or a year to write about something. One thing I’ve always loved about writing CTMQ is that I’m in complete control. It’s a crime that locally owned farms with operational silos are disappearing, but middle managers complaining about a work group being too “siloed” is epidemic. The title on this page, if you didn’t get it, is an homage of sorts to corporate-speak.
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Covid rash vaccine9/25/2023 These usually transient AEs are very frequently reported after COVID‐19 vaccinations as well. 1, 2, 3, 4, 5 General symptoms that have also frequently been observed after the use of other vaccines include fever, headache, fatigue, chills, muscle pain, diarrhoea and local injection‐site reactions. Hence, there is also increasing real‐world evidence on adverse events associated with the use of the new COVID‐19 vaccines. End of May 2021, over 1.5 billion vaccine doses have been administered worldwide. Most vaccines need two doses, except for Janssen COVID‐19 vaccine ® and Convidecia ®. All these vaccines have to be administered by intramuscular injection. 1, 2, 3, 4, 5 The vaccine platform of aforementioned vaccines includes mRNA, non‐replicating virus vector or inactivated virus material. However, there are other COVID‐19 vaccines, including Convidecia ® (CanSino Biologics), Sputnik V ® (Gamaleya Research Institute), CoronaVac ® (Sinovac), which have been approved by at least one country. Moreover, the vector‐based vaccine Janssen COVID‐19 vaccine ® (Johnson & Johnson ) has now also been approved for use in Europe. Since December 2020, huge vaccination campaigns have been introduced in Europe, using first the mRNA vaccines Comirnaty ® (Pfizer/BioNTech BNT162b2) and Moderna ® (Moderna mRNA‐1273) and then also the viral vector‐based vaccine Vaxzevira ® (AstraZeneca AZD1222) which all have recently been approved by the European Medicines Agency. 1, 2, 3, 4, 5 According to the WHO COVID‐19 dashboard accessed on 1 June 2021, there have been more than 170 million confirmed cases of COVID‐19, including almost 3.6 million deaths. However, SARS‐CoV‐2‐specific and neutralizing antibodies decrease over about 8 months, raising concerns for long‐term protection and herd immunity post infection. Memory B cell as well as CD4+ lymphocyte responses can be detected in over 90% of patients up to 6 months after infection. A significant variability in the magnitude of adaptive immune responses has been observed in patients with COVID‐19. Apart from antibody formation, natural infection with SARS‐CoV‐2 also activates a T helper lymphocyte‐1 pronounced immune response with SP‐specific CD4+ lymphocytes. Hence, neutralizing antibodies are probably the main players in protection from the virus. Antibodies particularly binding to the receptor‐binding domain and the N‐terminal domain of SP can prevent virus attachment to cells finally resulting in neutralization of the pathogen. S1 includes the receptor‐binding domain finally binding to the ACE‐2 receptor. Subunits (S1, S2) of the trimeric SP are involved in receptor binding as well as membrane fusion activity. Via the SARS‐CoV‐2 spike protein (SP) at the virus surface, the pathogen is capable to enter human cells by binding to the angiotensin‐converting enzyme‐2 (ACE‐2). As a result of the very fast spread of the disease throughout the globe, the World Health Organization (WHO) declared COVID‐19 a pandemic on March 2020. In the end of December 2019, a novel coronavirus disease (COVID‐19) caused by the severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) emerged in China. the spike‐protein sequences used to design the vaccines) and human components and may thus explain some COVID‐19 pathologies as well as adverse skin reactions to COVID‐19 vaccinations. Importantly, molecular mimicry exists between SARS‐CoV‐2 (e.g. In conclusion, there are numerous cutaneous reaction patterns that may occur following COVID‐19 vaccination, whereby many of these skin findings are of immunological/autoimmunological nature. Pityriasis rosea‐like rashes and reactivation of herpes zoster have also been reported after COVID‐19 vaccination. Functional angiopathies (chilblain‐like lesions, erythromelalgia) may also be observed. Autoimmune‐mediated skin findings after COVID‐19 vaccination include leucocytoclastic vasculitis, lupus erythematosus and immune thrombocytopenia. Type IV hypersensitivity reactions may be observed, including delayed large local skin lesions (“COVID arm”), inflammatory reactions in dermal filler or previous radiation sites or even old BCG scars, and more commonly morbilliform and erythema multiforme‐like rashes. urticaria, angio‐oedema and anaphylaxis) likely due to allergy to ingredients may rarely occur but can be severe. Unspecific injection‐site reactions very early occurring after the vaccination are most frequent. In this review article, we provide a brief overview on cutaneous findings that have been observed since the emerging mass COVID‐19 vaccination campaigns all over the world. There is growing evidence that not only the novel coronavirus disease (COVID‐19) but also the COVID‐19 vaccines can cause a variety of skin reactions.
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Sanus curved tv stands with mount9/25/2023 Crawford's Superstore may deduct the shipping charge from any subsequent refund, even if the original transaction included free shipping. Shipping and handling charges are not refundable. Please include a full explanation in the email as to why you are requesting the RMA. All returned items must be in be in brand new and unused condition, with all original tags and labels attached. Please see below for more information on our return policy.Īll returns must be postmarked within 30 days of the purchase date. However, if you are not completely satisfied with your purchase for some reason, you may return it to us for an exchange or refund. We hope you are happy with your purchase. Keep all the product packaging. You'll need it if you have to return or move your item. The delivery driver will not help you unpack or set up your new equipment, nor will he or she remove your old equipment or packaging. What to expect from the delivery driver. This is a large, heavy item, so arrange to have someone else there to help you unpack and install your equipment. Freight deliveries are scheduled for Mon through Fri between 9AM and 5PM. Someone will have to be on hand to meet the driver and sign for the package. Someone must receive the delivery. The freight carrier will contact you to schedule delivery to your door or the lobby area of your apartment or condo. Large or heavy items, including most TVs, require freight shipping and generally take a little longer to be delivered, contact us for delivery estimates. For all other shipping options please call for more details direct during Business hours Mon to Fri 10am to 5pm EST Tel: 18. Exclusions apply to orders shipping to APO/FPO addresses, Puerto Rico, Hawaii, Alaska and other U.S. FREE SHIPPING within the 48 contiguous states in the USA only.
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Zebra tattoo designs9/25/2023 You can have this tattoo in any size however, it will look great in small size etched on your arm. A simple zebra etched on your arm will look stunning. If you’re looking for a simple animal tattoo design, then a simple zebra tattoo idea is apt for you. You might choose to have a zebra tattoo as a representation of your attractiveness, or if you possess all of these traits, then surely a zebra tattoo design is apt for you. They stand out from other pack animals because of this particular trait of theirs.As a consequence of this, zebra tattoos are fantastic representations of one’s personality and sense of autonomy.Ī Zebra tattoo can also be a symbol of finding harmony in life. They travel in herds to stay together in order to stay alive. When we say strength, it includes both mental and physical strength.Īside from that, zebras also represent unity as they travel in herds. People who want to showcase their strong side are the right candidates for zebra tattoo designs. Their kicks are just as powerful as those of horses.Ī zebra tattoo can symbolize myriads of things, including strength, independence, unity, and harmony. However, you may be surprised to know that they can kick and bite. Due to the zebra’s reputation for not being a particularly hostile animal, most people are unaware of its formidable capabilities. These black and grey striped animals look cool. Let’s now take a look at the zebra tattoo symbolism along with different zebra tattoo ideas. Zebra tattoos carry significant connotations, even when they are not among the most common animal tattoos. There is no doubt that zebra tattoos are pretty popular due to their distinct appearance and personalities. Once they have selected their partners, they remain loyal to their partners. These black and white striped animal blend in very well with their surroundings. Compared to other animals, zebras have a more diminutive build. They are widely considered to be one of the most distinctive and eye-catching animals. Zebras are certainly the best-dressed creatures. This exotic animal can be a great choice for people who love animals and want to showcase their love for them. If you have given a lot of thought to your next tattoo design, but couldn’t decide on one, then a zebra tattoo is your best bet. Zebra tattoos have become an increasingly popular choice for people to get inked. These beautiful looking animals make for stunning tattoo designs. So, without any further ado, let’s get started… In this post, we are sharing some of the most beautiful zebra tattoo designs with you to help you get some insight into Zebra print tattoos. Have you ever imagined having a Zebra print tattoo?Īnd trust you’ve landed on the right platform to get zebra tattoo ideas.
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To make this list into a single piece of text with one city per line, use the list that contains city names only set the text item delimiters to linefeed then coerce the list to text. This returns a list of all the city names (or a list of lists of IP address-city name pairs if you elect to use the line I commented out as an alternative). Set URLQueryString to "?access_key=" & the APIKey & "&fields=city" After the repeat loop is complete, your final command would simply be a reference to that list so as to have AppleScript evaluate its contents and return the result: set APIKey to "" You can do this by first declaring a variable as an empty list, into which you would add an item of data in each iteration of your repeat loop. Custom scripting is usually required to manipulate text with AppleScript. Overall, JavaScript has a much wider-range of built-in language-level text manipulation functions. The problem is that I don't know how to control (exec line by line, debug, etc.) AppleScript execution, if it's possible at all. AppleScript and JavaScript both possess some basic text manipulation functions and properties that allow you to concatenate text, get the length of a string, and more. For this, own scripting language can be left untouched, but mapping to AppleScript can be added. So for a more comprehensive solution, you can edit your script slightly so that the last command will be one that returns what you actually want. And also to engane AppleScript as much as possible. The final command in your script will be set cityName to city of json, and so the result of your script will be the value of cityName after it has been set to the value from the JSON record that pertains specifically to the last IP address in your list, i.e. It will print a live result from each AppleScript command executed during the run of a script, whereas the Results pane only returns the overall result of the script's execution (which equates to the result of only the final command). The immediate solution would be to use the Replies pane rather than the Results pane in Script Editor.
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One piece odyssey locations9/25/2023 There’s a gargantuan squirrel enemy with a malicious smile that sticks its tongue out like a goofball. Animal designs expertly mix campy and vicious elements. The environments and characters are the best they’ve ever looked in any One Piece game, with Dressrosa and Marineford Town as standout locations. On the bright side, Odyssey’s art direction does a great job mimicking the source material. Odyssey’s vivid take on the One Piece world makes its navigation and pacing issues even more exhausting by contrast They halt Odyssey’s momentum at nearly every turn. They’re especially prevalent during puzzle sections in which you have to quickly go between multiple areas. Short one-to-two-second loading screens frequently obstruct progress at crucial points. This monotonous design is heightened by poor optimization. Levels are tedious, filled with mundane, mandatory fetch quests, like locating a desert bandit who has stolen the crew’s food or defeating an unnamed outlaw to claim their bounty. Odyssey doesn’t respect the player’s time in the design sense, either. Conversely, Odyssey features too little information on each arc for potential fans to gravitate toward without prior context. Dressrosa - the most recent arc included in Odyssey - was originally published from 2013 to 2015 and has been featured in numerous recap specials. These stories are old hat to longtime fans. This is simultaneously a horrible way to relive One Piece and to dive into its world for the first time. It’s unclear what audience was in mind during Odyssey’s development. To regain their skills, the Straw Hats need to explore the mysterious “world of memory.” This functions as an excuse to lead players through re-creations of iconic moments from One Piece’s 25-year history.Ĩ things you should know about One Piece Odyssey Upon spotting the crew, Lim preemptively uses her abilities to remove the group’s memories of how to fight. Like most rational people, Lim doesn’t trust pirates. The island has only two inhabitants: an adventurer named Adio and his surrogate daughter, Lim. In One Piece Odyssey, the Straw Hat Pirates have been marooned on an island called Waford. To achieve this goal, Luffy and his crew, the Straw Hat Pirates, search the sea for a legendary treasure known as One Piece. Luffy’s journey to becoming King of the Pirates. A great RPG sits somewhere inside One Piece Odyssey, but it’s obstructed by numerous baffling choices. It’s composed of tailored moments for both casual and longtime fans, but the end result is a garbled adventure. To its detriment, One Piece Odyssey, the new JRPG from developer ILCA, tries to capitalize on that ubiquity by appealing to everyone, and as is often the case with this approach, it doesn’t feel geared toward anyone. The pirate-centric manga and anime series’ branding can be found in films, bath bombs, deodorant, and commercials for.
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Compare rawtherapee lightroom9/25/2023 And also I’m sure with a very quick Google search they’d find a multitude of open source projects that could produce a JPEG for printing. But I discovered something about Dolphin, the KDE file manager – it can already see DNGs! DNGs are visible in Dolphin Basically, JPEGs are everywhere so I am sure that my descendants will have access to the photos. First off, the reason I always create JPEGs of my DNGs is so that people can see my files even if they don’t use Lightroom or Photoshop. So I googled and I posted on forums and experimented. But perhaps there’s room for a new workflow. If I can keep it mostly the same, that helps in not wasting my time on a learning curve. Yesterday I posted my typical Adobe Lightroom RAW workflow. Even if performance is no better than Lightroom, I’m saving myself about $150 every 1-2 years (assuming they don’t end up forcing the subscription model as they’ve done with the Creative Suite). Finally, the software is free in all senses of the word. The btrfs file system has matured a lot and it has natural protections against bit rot (even moreso if you have a RAID1 or greater setup). For one, I get to use my dual monitor setup to perhaps light-table the images at a larger size. But can I do what I need to do with Linux? A coworker says his experience is the same with Lightroom post version 3. Things just take forever and that delay costs me free time. Without providing any noticeable improvements over 3, it is so slow and memory-intensive compared to 3. The problem is that Lightroom 5 is horrible. So I figured I’d be a Lightroom user for a few more years. But I’d had Lightroom 5 on my wishlist and someone bought it for me for Christmas. So while it’s cheaper to pay monthly than buying outright (at the prices they had when they went subscription), I rarely found the upgrades worth is and so was able to save some money. While there are surely some benefits to being able to rent Photoshop and Adobe’s awesome video editing software when you need to do a project rather than for a thousand-plus fee, one way I’ve afforded Lightroom is not upgrading every year. Lightroom is still available standalone, but it appears the rest of the CS suite (including, for example, Photoshop) are on the treadmill now. But Adobe seemed to be moving more and more towards a subscription-only model. Competition from Apple Aperture and other programs caused it to eventually drop to $150 per version. Back then I was making use of the student price to actually be able to afford it. Last Fall I started considering moving away from Lightroom after having used it for nearly a decade.
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Defcon schedule9/25/2023 A PDF allows for revisions, but it can be a complicated process, and isn't always possible due to other things contending for the same resources during DEF CON.īecause of these problems with a printed program, DEF CON Goons from the InfoBooth department have worked hard to build a dynamic and schedule which can be updated and made available online and revised as changes appear. It is hard to exploit a printed program, but also harder to update when content changes. The program is presently being designed and worked on. The original, official source of schedule has been a printed program provided when attendees pick up their badge, and then provided as a PDF people can download. From the main DEF CON website, on the right, you may see "Upcoming Events" - those are exported from the forums. The DEF CON Forum server exports a calendar for some things which have been scheduled. Entertainment: LasVegasShowsTonight.TL DR: the infobooth schedules are not ready yet and probably won't be ready until at least 1 week after a majority of speakers in main DEF CON tracks are selected.Look to the Bottom Right of this page now to start chatting. Where Else to Stay for DEFCON 2022?įor more information about Groundwater Week 2022 or any convention-related needs, call at 70 or chat live with us. Read Rajat Moury’s answer to How does one become a hacker? on Quora DEFCON 2022 Schedule How does one become a hacker? Here’s the answer. Be safe and have fun, everyone! Pls RT #dc28 /bYmCMf2B4D #DEFCON may be in Safe Mode this year, but we are still here to represent. Though Defcon 2020 was canceled, the spirit of hacking remains alive among its community members. If it works we get some more bandwidth for you dark web downloaders. Soon is going to try announcing the #defcon and onion addresses on different networks at the same time. See Photos From DEFCON Conversations About DEFCONīe up to date with the latest news and update about the association by following their Twitter page. Here are some highlights from a DEFCON event that was held in China.Ĭool shirt from DEFCON Hacking Conference! Here’s what you need to know about DEFCON safe mode. DEFCON 2022 Floor Plan Caesars Palace Las Vegas floor plan Photo by Smart VegasĬlick here for the detailed floor plan. How to Become a Sponsor in DEFCON 2022?Ĭlick this link to learn how to become a sponsor. How Many People Are Expected to Attend DEFCON 2022?Īpproximately 6,000 people How Many Exhibitors?Īpproximately 100 exhibitors Who is Speaking at DEFCON 2022?Ĭlick here for the full list and schedule of all the speakers for this event. As the saying goes, knowledge is power, which is what this event offers. Why You Should Attend DEFCON 2022Īttending DEFCON is your ticket to gaining the edge over your peers and competitors as an IT professional. Who Attends DEFCON?ĭEFCON is attended by hackers, IT professionals, and government employees working in cybersecurity. Gates open on Thursday, August 5, 9:30 am – 6:00 pm, and close Sunday, August 8 at 4:00 pm. Where Is DEFCON 2022 Held In?īally’s Las Vegas, Las Vegas, Nevada Where to Stay for DEFCON 2022? You’ll be able to learn cutting-edge hacking research and technology from the most brilliant minds in the world and test their skills in contests of hacking supremacy.Ĭlick this link to register for DEFCON 2022. If you aspire to become a player in this highly specialized niche, secure your seat before it runs out. This event is truly the largest underground hacking conference and will be life-changing for all its guests. So connect with our team of experts today! What Is DEFCON Conference?ĭEFCON is the premier event for hackers, corporate IT professionals, and government agencies aiming to expand their knowledge and skillset in the world of hacking. can take care of your entire experience–guests, transportation, hotels, and more. We pride ourselves on being the best at what we do, so let us help you prepare for a great time in Las Vegas! It’s a no-hassle experience that saves you time and money throughout your trip. Let us take care of everything for you! Our team of professional concierge specialists will connect you with everything you need for your trip.
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Schools for voice acting9/25/2023 What You Need to KnowĪudition guidelines are available on the PPA site. We provide training in voice-over, singing, public speaking and vocal health for both adults and kids. Our global graduates work in network television, studio films, animation series, Broadway, and streaming services worldwide. Students have booked professional acting opportunities while enrolled and have maintained internships with studios, agencies, casting offices, and theaters. Our mission is to provide education that blends personal development with the technique of acting to bolster voice actors, the creatives, in expanding your. Inner Artist Performance Studios in Atlanta offers exceptional voice acting classes designed to help you develop the skills necessary to become a versatile. You will apply your classroom learning in various productions, including a senior year showcase/capstone, and leave the program with a professional reel ready to navigate the New York or Los Angeles film and television industry. While enrolled, students will engage with working industry professionals and be given opportunities to build their networks. Acting for Film and Television VIII - Senior ShowcaseĪdd Opportunities and Experiences Leave With a Professional Reel. Courses are all taught by a diverse faculty comprising award-winning and major motion picture writers, directors, actors, and casting directors. Our program includes acting training on camera (film, television, and commercial), script analysis, vocal production/speech, physical preparation, voice-over technique, and film/television history, with hands-on training in content creation, podcasts, and new media. With a conservatory-like model, the FTVC major provides sequential training from day one.The FTVC major at Pace School of Performing Arts is the first undergraduate university program in the US founded exclusively for training the actor for work in front of the camera and microphone. Best Voice Acting Classes Online Best Overall: Introduction to the Voice-Over Industry from a Voice America Recognizes Best for Beginners: Learning Voice.You never know what you can achieve until you try. Let's get started, and see what the future might hold. They have learned every facet of the business. Many of my past students enjoy working in animation including anime, cartoons, and video games as a result of their studies. I have lived this career and want to share all of my knowledge with you. That includes improving the speaking and acting skills necessary to stand out in the competitive world of voice-acting. I AM THE REAL DEAL! A veteran voice actor who can help you develop your complete vocal style and sound. No special equipment is needed to begin your classes. You will learn how to make a voice demo, find work, and even create your own studio. It is a practical course where we work as in a recording studio, with a sound technician in the. The list includes radio/TV commercials, narrations, audiobooks, auditions, anime, video games, cartoons, and much more. Now you can train to be a Voice over actor at AM ESCUELA. Interactive classes give you a chance to voice actual professional scripts that I have personally recorded in all genres. If you're serious about starting a new career, or supplementing your income, join dozens of my students who have successfully completed this amazing course. Study voice acting one-on-one with a professional, experienced, award-winning voice talent. We can also explore how you can create your own basic home studio, including microphone, software, interface, computer, headphones, and sound blankets. We'll cover: vo markets how to develop leads how to cultivate clients what to expect from a client how to audition and how to deliver work that will make the client happy. We'll apply the elements of Voice Acting to the study of voice artistry, video game voiceovers, commercial voiceovers, audiobook narration, character voices, dialects, documentary vo, reading short stories, auditions, and more. We'll explore what to expect in the studio, how to work with a producer, how to work with a sound engineer, and how to work with other voice actors. We'll study how to prepare your script, including identifying and using key words, and script shorthand. We'll study mic technique, what to do and what to avoid. I teach all kinds of acting, and have for over 50 years, but I specialize in stage acting, on-camera acting, acting for the face, voice acting, comedic acting, physical acting, improv, script analysis, monologues, audition prep, audition videos and voice over auditions.įor Voice Acting, we'll cover the various elements including: pitch loudness speed rhythm tone prosody variables and variations character elements use of dramatic and comedic pauses emotion enunciation emphasis pace intervals nasal continuents u-glide musicality timing, and more.
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Fibrocystic breast changes ncbi9/25/2023 Cancerous breast masses rarely present with pain, although the presence of pain should not exclude neoplastic lesions from the differential. More important is to establish whether the mass had developed in association with trauma or other symptoms and how rapidly the mass appears to be growing or changing, if at all.Īn acutely tender breast lump is more likely to be an abscess or hematoma secondary to trauma. Indeed, a proportion of breast lumps are identified through routine screening, so this is not necessarily an accurate way of determining the acuity of such a mass. Patients who do not regularly carry out breast self-examination may take longer to notice a breast lump. It is not always possible to establish the duration for which the mass has been present. Particular emphasis should be placed on the chronological development of the lump and the symptoms associated with it. Ī thorough and accurate history is the cornerstone of approaching any new breast mass. Other risk factors, such as excess alcohol intake and obesity, are thought to increase endogenous estrogens. Male patients should be asked about previous hormonal treatments for prostate cancer, the use of finasteride or testosterone, episodes of orchitis/epididymitis, or previously diagnosed Klinefelter syndrome. Early age of menarche, late age of first pregnancy, nulliparity, oral contraceptive or hormone replacement therapy, and late menopause increase estrogen exposure, while breastfeeding is a protective factor. Therefore, it is essential to interrogate lifetime estrogen exposure in all patients presenting a new breast mass. The primary risk factor for developing breast cancer is excess exposure to estrogens. Breast tissues, and indeed the majority of breast pathologies, are responsive to changes in hormone levels. Breast tissues involute significantly following menopause, the glandular tissue atrophies due to the reduction of circulating estrogen levels and is largely replaced by fatty tissue. īreast tissue is present in children and males but is more developed in females of reproductive age due to hormonal surges that arise at puberty. Lymphatic drainage is primarily through the axillary lymph nodes and involves the pectoral, subscapular, and internal mammary nodes. The lobes are supported by fibrous stroma and fatty stroma. Each breast has 15 to 20 lobes, which are drained by lactiferous ducts that converge beneath the nipple in the subareolar region. The breast, or mammary gland, is a modified sweat gland containing various fibrous tissue, glandular tissue, and adipose tissue. Such an approach will be described in this article, with examples throughout of the common breast pathologies encountered. In general, the approach should follow the triple-assessment pathway of clinical examination, radiological imaging, and pathology analysis. īreast cancer is the most common type of cancer in women worldwide, with an incidence of approximately 12%, and therefore although the vast majority of breast lumps are benign, a thorough and structured approach is required in all cases. Indeed, male breast cancer is a well-documented condition and requires a considered index of suspicion for its timely diagnosis and intervention. Although the majority of breast masses present in adult women, children and men can also be affected. Breast masses have a wide range of causes, from physiological adenosis to highly aggressive malignancy. Over 25% of women are affected by breast disease in their lifetime, and the vast majority of these cases will present initially as a new breast mass in the primary care setting. Breast lumps or masses are very common, particularly among women of reproductive age. |